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Reagent Storage Chest
I know of 16 creatures that drop Plague. There could be more, I don't have the scoop on ALL the bosses out there yet. I been trying to get Valdus to do my work for me - uh, I mean HELP me, but I haven't had much luck yet.

Akhtang WormCrawlCastle Darkmoor, Wizard City
Bane WyrmCaliburn, Avalon
Caquix Nine Shadows Mangrove Marsh, Azteca
Count Bela BlackSleep Castle Darkmoor, Wizard City
Doctor JackallBarkingham Palace, Marleybone
Drowned Knight Deepwater, Avalon
LoremasterThe Atheneum, Dragonspyre
Morag BloodtineCaer Lyon, Avalon
Murat GreyeyesElephant Graveyard, Zafaria
Noxious Gas GolemBarkingham Palace, Marleybone
Pendragon Outer Yard, Avalon
Shane von Shane Castle Darkmoor, Wizard City
Shane von Shane (Star) Castle Darkmoor, Wizard City
Sir Blackwater Castle Darkmoor, Wizard City
Yevgeny NightCreeper Castle Darkmoor, Wizard City
Young MorgantheCrystal Caves, Avalon